World TB Day 2022 is an important reminder of one of the world’s top infectious killers. For the first time in more than a decade, deaths attributed to tuberculosis (TB) increased in 2020, based on data reported by the Pan American Health Organisation (PAHO). The disease is estimated to have killed 1.5 million people globally in 2020. 1
TB is among several disease categories that has suffered from reduced testing rates due to the pandemic response due to reallocation of staff and resources, and changes to care-seeking behaviour. Of the 9.9 million people estimated to have contracted TB in 2020, only 5.8 million were reported, down from 7.1 million in 2019. 1
The widening diagnostic gap threatens to undo decades of progress made by international public health strategies. Only 1 in 3 of drug-resistant TB cases were able to access treatment in 2020, down 15% from 2019. 1
Early detection is critical for the effective treatment and suppression of TB. AusDiagnostics produce two TandemPlex® diagnostic panels that target Mycobacterium tuberculosis (MTB) complex to enable syndromic testing. Incorporating gene targets for pathogens that confer analogous symptoms, AusDiagnostics’ Pneumonia 16-well and CSF 16-well enable clinicians to distinguish TB from other clinically-relevant pathogens, enabling early medical intervention.
Pneumonia 16-well |
Targets: Bacteria Mycobacterium tuberculosis (MTB) complex Mycoplasma pneumoniae Bordetella pertussis (IS481) Coxiella burnetii Chlamydophila pneumoniae Chlamydophila psittaci Haemophilus influenzae, H. parainfluenzae & H. haemolyticus Legionella pneumophila Legionella longbeachae Streptococcus pneumoniae Staphylococcus aureus |
Fungi Aspergillus fumigatus Pneumocystis jirovecii (PCP) Cryptococcus neoformans |
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CSF 16-well |
Targets: Bacteria Mycobacterium tuberculosis (MTB) complex Haemophilus influenzae Leptospira interrogans Listeria monocytogenes Neisseria meningitidis (2 assays) Streptococcus pneumoniae |
Yeasts Cryptococcus neoformans Viruses HSV-1 HSV-2 VZV EBV Enterovirus Parechovirus |
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Banner credit: Pan American Health Organisation