September 2024 Newsletter

In this edition

 
 
 


A look at our parent company, R‑Biopharm

AusDiagnostics has now been part of the R-Biopharm family for more than 2 years. The pace of our partnership has since advanced by leaps and bounds, fulfilling our objective of providing our diagnostics to the markets who need them.

As our business operations have begun to intermingle, the AusDiagnostics community have been asking who R‑Biopharm are and how our customers are benefiting from the partnership.

R‑Biopharm is a leading supplier of reliable test solutions for clinical diagnostics, food & feed analysis and precision medicine. In its 36 years of operation, R‑Biopharm has grown to over 1,400 employees worldwide and is successfully represented in more than 120 countries through 120 distributors and 29 subsidiaries.

AusDiagnostics have been able to enjoy the vast distribution network of our parent company. Through leveraging R‑Biopharm’s local knowledge of the healthcare industry and regulatory landscapes, more countries than ever have been able to access our highly multiplexed diagnostics and automation technologies. Conversely, our expertise and experience with the Australian, Asian, Pacific, and American markets has been instrumental in delivering the broad portfolio of R‑Biopharm diagnostics to those customers.

Our community can benefit from new dimensions of diagnostics, ranging from clinical diagnostics to food & feed analysis across the entire nutritional food chain, in addition to supporting precision nutrition care.

We are thrilled to see the benefits of our partnership already precipitating across the globe. Expect to see more collaboration between AusDiagnostics and R‑Biopharm in the future. In the meantime, we invite you to join the R‑Biopharm community to stay up to date with our joint mission for quality diagnostics worldwide.

 

      

 
 
 

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The Award-Winning HighPlex Ascend

(Coming Soon)

Quality is not merely a standard, but a continuously evolving process. It is the motivation for innovative ideas and all the efforts needed to bring them to life.

Last quarter, we announced the HighPlex Ascend; The next iteration of our most popular MT-PCR automation platform. Trusted by laboratories as an everyday diagnostics workhorse, the classic HighPlex is synonymous with quality and reliability. The HighPlex Ascend* was the culmination of decades of experience and a multidisciplinary collaboration of design and diagnostics experts, sharing a singular vision of quality automation.


Video Credit: Design Anthology

The effect of these innovations has now been recognised. We are thrilled to share that the HighPlex Ascend* is a Good Design Award winner in the categories of Engineering and Product Design.

The award, presented by Good Design Australia, was justified with reference to the 95% reduction in the number of parts comprising the HighPlex Ascend* compared to its predecessor, improving reliability of quality assurance passes. The lower part count is one factor contributing to a 163% efficiency improvement for assembly, calibration, and commissioning.

Additionally, the new design features a range of usability improvements, such as visibility of the instrument deck and status lights, improved component accessibility, and a simple, easy-open instrument canopy.

The award is a testament to the AusDiagnostics team’s commitment to continuous improvement, and their wealth of skill and expertise.

 

Read More       View HighPlex Ascend

* The HighPlex Ascend is coming soon. 
 
 

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Improvements to our Respiratory panels

We are committed to continuously improving our products and services based on user feedback. As a result of careful post-market surveillance, we are thrilled to share several upcoming improvements to our range of Respiratory TandemPlex® panels.

The product changes were communicated to existing customers in a detailed advisory notice, and will improve the specificity, genotype inclusivity, non‑specific background amplification, robustness, and stability of certain assays.

Seemingly every newsletter we publish includes an extensive list of product updates. Behind each list lies an enormous effort by our Research & Development, Quality Assurance, and Product Management teams to understand the plight of our customers and translate their challenges into tangible improvements.

We would like to thank our customers for your continued support and collaboration in improving our panels and uplifting patient outcomes.

 

View Respiratory Panels

 
 
 

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Solutions for vector-borne pathogens testing

Vector-borne tropical diseases may be caused by a range of viral, bacterial, or protozoan pathogens. The number of candidates and the required range of diagnostic sensitivity poses a challenge for clinicians.

We recently launched our Vector-Borne Disease portfolio, a meaningful step toward supporting the response to neglected tropical diseases.

The pair of TandemPlex® panels enable clinicians to perform differential diagnostics of syndromically-relevant pathogens spread by mosquitos and livestock.

Mosquito Borne 16-well*
(RUO)
REF 27157.8

Vector Borne 16-well*
(RUO)(Coming soon)
REF 27157.9

Viruses
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Ross river virus
Chikungunya
Barmah forest virus
West Nile virus
Zika Virus
Murray valley virus
Japanese Encephalitis
Kunjin virus
 
Protozoan parasites
Plasmodium spp.
 
Antimicrobial resistance
Artemisinin Resistance

Viruses
Dengue virus 1
Dengue virus 2
Dengue virus 3
Dengue virus 4
Chikungunya
West Nile virus
Zika Virus
Murray valley virus
Japanese Encephalitis (inc. Genotype 5)
Kunjin virus
 
Protozoan parasites
Plasmodium spp.
Plasmodium alciparum
Plasmodium vivax
 
Bacteria
Leptospira interrogans

 

View Panels

* The Vector-Borne Disease panels are intended for research use only. Not for use in diagnostic procedures. 
 
 

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Mpox global health emergency

The AusDiagnostics team has been closely monitoring the spread of mpox as the World Health Organization (WHO) declared a public health emergency of international concern (PHEIC) in response to a worrying increase in transmission.

Monkeypox virus is a lesion-causing virus that readily transmits via skin-to-skin contact. Those with underlying health conditions, especially immunocompromised people, are more likely to experience a higher severity of infection and greater risk of fatality.

WHO cited a novel subclade of Monkeypox to justify an internationally coordinated effort to quell the outbreak. The new subclade, designated Ib, is expected to exhibit a high likelihood of infection for close contacts of confirmed cases according to the European Centre for Disease Prevention and Control (ECDC).

As health authorities in Europe, UK, USA, and Australia prepare for the arrival of mpox, consider integrating multiplexed syndromic screening into your service offering with the AusDiagnostics Lesions and Ulcers 12-well* panel.

 

Read More       View Panel

* The Lesions and Ulcers 12-well (REF 87191) panel is intended for research use only. Not for use in diagnostic procedures. 
 
 

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Workflow Comparison: Extraction-free PCR, or parallel extraction?

As laboratories contend with the unending struggle to optimise their diagnostic workflow, it pays to challenge long-standing conventions and consider a range of alternatives.

 

Parallel Processing

Users of AusDiagnostics instruments will be familiar with parallel processing. Primary samples are loaded onto an extractor for purification, before being transferred to a PCR processor for amplification and analysis.

Parallel processing has the advantage of simultaneous utilisation of multiple specialised instruments. When all the instruments in a parallel processing workflow are aligned, runtime is generally optimised and operational simultaneity reduces instrument downtime, creating a powerful improvement in throughput over the course of a workday.

 

Extraction-Free Processing

The need for an extraction protocol can be eliminated with an appropriate pre-treatment step. The pre-treatment is usually specific to a similar group of targets such as gastrointestinal pathogens, making extraction-free workflows well-suited for multiplexed PCR diagnostics.

By eliminating the need for lengthy extraction protocols, important samples can be fast-tracked without sacrificing amplification quality. Without an extractor, extraction-free processing frees up valuable bench-space for additional processors or other equipment.

 

Versatile Processing

Tactical switching between the parallel and extraction-free configurations ensures your laboratory is always able to leverage the optimal workflow for a given situation.

Adapting your PCR processor from parallel to an extraction-free configuration can free your extractor for other important processes in the lab, and allows for more rapid screening of targets compatible with pre-treatment protocols. Alternatively, changing to parallel processing ensures maximum throughput when testing for a range of different targets simultaneously.

The UltraPlex Jump* (RUO, Coming soon) enables diagnosticians to tactically swap between parallel and extraction-free capabilities for compatible targets, conferring the versatility to select the best workflow for your laboratory’s evolving demands.

 
 

UltraPlex Jump*

UltraPlex Alliance™*

(Coming soon)

(Coming soon)

Automate highly-multiplexed PCR without the need for extraction.

Align the capabilities of a high-throughput extractor and MT-PCR processor.

Extraction-Free Protocol

Parallel Processing Workflow

96 Samples per run

96 Samples per run

Compatible with a broad range of targets from the Gastrointestinal TandemPlex® portfolio

Compatible with all TandemPlex® targets

Learn More Learn More

* This product is intended for research use only. Not for use in diagnostic procedures. 
 
 

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Company Culture Highlights

September was marked by our much-anticipated annual Corporate Games. This year, the team unleashed their competitive spirit with a dodgeball tournament.

The team also took a morning to recognise RUOK day, sharing important mental health check-in conversations over a barbecue brunch.

As part of a shift toward charitable activities, our New Zealand team spent their team-bonding day with Glen Innes, a decile 1 low-socioeconomic school. The team brought some poems, cards, and books, and spoke with staff to better understand the plight of students learning in underprivileged areas. The New Zealand team received several thank you cards from the students.

 
 
 

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Join a network of diagnostics professionals

Our social media community is a unique blend of professionals from clinical and non-clinical backgrounds. Following AusDiagnostics on social media is the perfect way to connect with an up-to-date network of peers to discuss the latest updates in the diagnostics world.

 

 

In case you missed it, here is a taste of our recent updates from Linkedin.

   
 
 
 

 
 
 

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